80% of Gastric Bypass patients Vitamin D Defficient
Obes Surg. 2009 May;19(5):590-4. Epub 2008 Oct 11.
Vitamin D status before Roux-en-Y and efficacy of prophylactic and therapeutic doses of vitamin D in patients after Roux-en-Y gastric bypass surgery.
Mahlay NF, Verka LG, Thomsen K, Merugu S, Salomone M.
Saint Vincent Charity Hospital, 2351 East 22nd St., Cleveland, OH, 44115, USA.
BACKGROUND: Literature regarding the effect of Roux-en-Y gastric bypass (RYGBP) on vitamin D level shows contradictory findings.
Our goal was to determine preoperatively vitamin D levels, to evaluate the efficacy of therapeutic and prophylactic doses of vitamin D and to assess the relationship of 25-OH vitamin D level and body mass index (BMI).
METHODS: We conducted a retrospective cross-sectional study of 72 patients who underwent RYGBP from April 2007 to October 2007 in Bariatric Surgery Department at Saint Vincent Charity Hospital.
RESULTS:
Our study demonstrated that ** 80% ** of the obese patients undergoing RYGBP had serum 25-OH vitamin D levels of less than 32 ng/ml.
(many laboratories currently have listed their normal range as 32-150 ng/ml)
Postoperative data show that 45% of these patients continue being vitamin D insufficient despite the treatment.
We demonstrated that a statistically significant inverse correlation between BMI and 25-OH vitamin D levels (r = 0.464, p = 0.01) exists.
I.e. Heavier patients = Lower Vitamin D
CONCLUSION: Our finding strongly supports the need for aggressive monitoring of vitamin D levels for long-term prevention of complications of vitamin D deficiency in gastric bypass patients.
Identifying the factors that predict patient's responses to vitamin D supplementation requires larger-scale studies and further analysis of these tendencies suggested by our findings.
PMID: 18850253 [PubMed - in proces
http://www.ncbi.nlm.nih.gov/pubmed/18850253
posted by DrR @ 7:00 PM
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